# medication timing

**URL:** <https://forum.barbellmedicine.com/t/medication-timing/12861>\
**Category:** Medical Q&A \[Moderated\]\
**Created:** [September 20, 2022, 5:02pm UTC](https://forum.barbellmedicine.com/t/medication-timing/12861 "2022-09-20T17:02:08Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Blackest\_eyes78](https://sea1.discourse-cdn.com/flex001/user_avatar/forum.barbellmedicine.com/blackest_eyes78/32/632_2.png) [@Blackest\_eyes78](https://forum.barbellmedicine.com/u/Blackest_eyes78)\
**Post date:** [September 20, 2022, 5:02pm UTC](https://forum.barbellmedicine.com/t/medication-timing/12861/1 "2022-09-20T17:02:08Z")

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Hello Docs! I’ve got a question about medication timing around a training session. Meds are Synjardy(dr recommended over just metformin cause of family history), lisinopril/hctz, and atovastatin. My main question has to do with synjardy and lisinopril. Would it be best to take these before or after training? I train in the morning after breakfast. I usually take them before but today I decided to take them after. I feel like i got more out of my session today than I have since starting the meds 4 months ago. Is this placebo or is it more nuanced. What do?

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**Author:** ![Austin\_Baraki](https://sea1.discourse-cdn.com/flex001/user_avatar/forum.barbellmedicine.com/austin_baraki/32/1095_2.png) [@Austin\_Baraki](https://forum.barbellmedicine.com/u/Austin_Baraki)\
**Post date:** [September 20, 2022, 5:13pm UTC](https://forum.barbellmedicine.com/t/medication-timing/12861/2 "2022-09-20T17:13:19Z")

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Using lisinopril as an example, its onset of action is within an hour, its half life is about 12 hours, and its overall duration of effect is about 24-30 hours. Meaning that whether you take it an hour earlier (e.g., before training) or an hour after (e.g., after training), it probably doesn’t make a huge difference and is in your system either way.

If you “felt” better taking it after, there is no downside to continuing to do this if it’s a sustainable strategy for you, and if it doesn’t cause you to develop symptomatic low blood pressure after training.