I’m trying to wrap my head around how data are collected for Mendelian randomization. I understand the concept of the GWAS database, but I’m not quite getting where that information originates. Is it just from individuals who have been involved in previous research projects who have submitted to their genetic material being stored for future study?
Yes, it is typically derived from large datasets including genetic information as well as numerous other biomarkers, for example the UK Biobank.
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