Could creatine negatively affect my thyroid, and tips on lowering progesterone

Medical Q&A [Moderated]
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Hello! I’ve been having health issues for a very long time, including untreated depression. I’ve finally decided to do something about it. My doctor prescribed me 5mg of escitalopram, and I’m also planning to get on bupropion 150mg soon (it’s not available in my country).

We did some tests. My testosterone is great (thanks to BBM) - 31.62 nmol/l; SHBG is 33.38 nmol/l; and my free testosterone index is 94.73% (maximum is 95%). All hormones that we checked were more or less fine, except progesterone which is 2.38 ng/ml. Which is more than two times higher than it should be.

We decided to check my thyroid and it turns out that I have issues there too. My Anti-hTg is 103.80 MOd/ml (it should be below 60), and my T-3 is 3.90 nmol/l (should be 1.25-3.03).

My question is could creatine be one of the causes of my issues? I’ve been taking it 3g every day non stop for about 3-4 years now, should I take a break from it for now?
Also what would you recommend I do about my high progesterone levels? My doctor gave my a bunch of vitamins, but I’m not sure they can help drop my progesterone. He told me that all my problems are stress/depression related, and I don’t need any hormonal therapy or anything serious like that. And he’s planning to prescribe me some Selenium for my thyroid, but he’s checking up with another doc atm, about what would be better for me to take.

I was hoping for a second opinion from you guys. Thank you.

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This is likely beyond the scope of this forum, and more likely involves individualized consultation.

I will say that Creatine is very unlikely to be related to any of your issues. It is unclear to me why your progesterone level was measured at all (it probably shouldn’t have been checked at all), and there are no specific therapies I would recommend for that.

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Alright, thank you for the answer Austin!

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Oh I guess I should’ve mentioned that aside from depression, I’ve had zero libido, was having sleep problems, minor restless legs syndrome, and it’s really easy for me to get sick especially when it’s getting cold outside.
Which is why we’ve checked all the hormones, including those that are related to thyroid, hypophysis, and adrenal gland.

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These are still not a good reason to measure progesterone levels in a male.

I would recommend continued follow up with your physician and, if necessary, you could pursue a second opinion from an endocrinologist.

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I see, thank you Austin!