Read that weight loss can contribute to increased risk for thrombotic activity followed by a suggestion that dieters consider taking low dose aspirin or fish oil to mitigate this tendency. Naturally, no citations, or specified studies.
Looked around on the internet, but came up short – this seemed to be the best of what I saw - attached table of hazard rations
Conversely, weight gain may lead to increased risk of VTE. Actually, several studies have shown that weight gain, weight loss and/or fluctuations in body weight are all associated with future risk of arterial cardiovascular diseases as well as all-cause mortality [10–17].
Weight loss and weight variability is associated with increased risk of cardiovascular disease, overall and cardiovascular mortality [12–14]. However, several reviews and meta-analyses have pointed out that the effects of intentional weight loss on these outcomes are uncertain [16, 41, 42], and confounding by concomitant illness may be of importance. The observed increase in risk of provoked VTE by weight loss in our cohort was not attenuated by exclusion of subjects with cancer, suggesting that cancer development did not contribute profoundly to the apparent association between weight loss and VTE risk.
Imagine that blood chemistry is altered whether you gaining or losing, but the increased risk for thrombotic behavior during weight loss seems counter-intuitive.
Does this recommendation to take aspirin or omega-3 fish oil during a prolonged campaign of weight loss make sense to you? Or is it just internet drivel and blather?
This article does not specifically look at such risks in the context of intentional weight loss (i.e., dieting, as you note in your thread title). It is simply looking at an association between weight loss in general, which, as the authors note, can be confounded by many things. They mention that excluding subjects with cancer did not attenuate the observed increase in risk, but there are still innumerable other medical conditions/contexts in which an individual may unintentionally lose weight due to an underlying medical condition that itself increases the risk of thrombosis.
In order to address your specific question, you would want to look at prospective weight loss trials and look for an increased incidence of VTE in the intervention group.
[quote=“Austin Baraki, post:2, topic:7142, username:Austin_Baraki”]
In order to address your specific question, you would want to look at prospective weight loss trials and look for an increased incidence of VTE in the intervention group.
[/quote]
thanks, dr. baraka – found the LookAHEAD study (still underway), which promises to be helpful
one thing for sure, my “quest” has sure crushed any delusions about weight loss being THE silver bullet I once believed it to be; and what I used to think was common sense is sure taking a beating
However, although the risks of overweight and obesity are generally well accepted, ## there is some controversy as to whether weight loss is beneficial### .The popular view is that weight loss is good for you but not all scientists believe that to be the case. Detractors note that a number of observational epidemiological studies have associated weight loss with increased mortality.
https://academic.oup.com/eurheartjsupp/article/7/suppl_L/L27/464319
this exercise in attempting to answer my own questions is 9-parts pounding sand to 1-part eureka…i suppose that ration applies to all learning
prompts reiteration of hope that BBM will one day offer an article, video, 2-minute Tuesday or seminar component covering search strategies which would make us more self-sufficient on the forum – hopefully, even in time for the san diego seminar 
thanks for pointing me in the right direction
How much of this paper did you read? The exact same concerns apply here.
The evidence from observational studies is conflicting: some studies have shown weight loss to be associated with increased mortality, but this could be because differentiation was not made between intentional and unintentional weight loss.
i.e., it should be obvious that ON AVERAGE we would not see benefits if we were including people who are obese and dieting intentionally alongside patients with cancer who are “dieting” unintentionally.