Link between Depression and Inflammation?

Medical Q&A [Moderated]
1

Is there good evidence of a link between depression and inflammation? I’m doing heavy volume work (legs/push/pull) for hypertrophy. I just started on a new program, and I noticed depression come back, though I can’t say it’s because of that. The SSRI I was taking was working, but as I introduced this new heavier volume, I’ve definitely noticed fatigue/depression. Perhaps it’s the fatigue that is linked to depression, more so than the inflammation? I was thinking that body inflammation keeps me from getting quality sleep.

I appreciate your thoughts.

2

Kind of, but probably not related to your training. Additionally, we cannot reduce depression down to being “caused” by inflammation anymore than we can reduce back pain down to a single thing. We expect depression, fatigue, etc. to ebb and flow over time.

We would recommend talking to your doctor about any new depressive symptoms you may be having.