Palmitoylethanolamide Supplementation

Hi docs,

Apologies for a possibly unnecessary thread, tried to search this but the search function didn’t like the term.

Have been through multiple bouts of testing for rheumatic conditions and things come up normal; have previously gone through the proclivity to pain I seem to have in another thread. Long story short, had this recommended to me by my family doc and is apparently used at the pain clinic here. Tried to scan through literature and it seems there’s some data on it that indicates more significant reductions than other supplements, but like with most others high quality evidence is lacking.

Any comments on this as a supplement for turning down volume on symptoms where an obvious pathology is lacking? Obviously main line strategy is sleep/stress reduction, not overshooting RPE or relying on stimulants for workouts, good dietary pattern with minimal refined foods, etc. Thanks in advance!

Unfortunately I don’t have any knowledge of, or experience with this supplement. Sorry.

No worries, thanks for your time.

PS: In case of interest, it seems to go by Palmidrol as well. Would be curious to know what you and Jordan think if you ever end up diving into it.