So after my annual physical this year, I was called back to get an additional blood test due to a high ALP level. After the second blood test, the voicemail they left me says “It looks like its coming from your bone production” and that they are scheduling me for a bone scan. I should say that I have no symptoms that I’m aware of, feel perfectly fit.
I googled around a bit and tried to determine if this result could potentially be from training. I didn’t train the morning of either test, but had done so 1 or 2 days before each and I’ve heard you guys mention these kinds of effects before. It seems like from what I read, this is not amongst the liver enzyme levels affected by resistance training, but I have no expertise here and really don’t know how to research this.
So my question is, without the actual lab result numbers, which I would need to go back there to get, can you tell me whether this kind of result that could be influenced by training? I’ll mention it to my PA, of course, but no idea if they would know the significance of it, if any.
Hope its not too vague… I’ll get the labs to post when I can.
This isn’t one that we commonly think of as being elevated from routine exercise. There’s a general Alkaline Phosphatase test, but since this enzyme has roles in a number of organs, there is a subsequent test for the Alkaline Phosphatase isoenzymes, which allows us to specifically differentiate from bone-related causes versus, say, liver/biliary system causes. It’s unclear from your post whether they did the isoenzyme test. There is a long list of potential causes for elevations in these labs, which may indeed need further evaluation, depending on the degree of elevation.
I’m 36. Here is the followup test result for isoenzymes:
Tests: (1) ALKALINE PHOSPHATASE ISOENZYMES (231) ALKALINE PHOSPHATASE 195 U/L 40-115 *1 Tests: (2) ISOENZYME PATTERN (%SB231) ! INTESTINAL ISOENZYMES 6 % 1-24 *2 ! BONE ISOENZYMES 74 % 28-66 ! LIVER ISOENZYMES [L] 20 % 25-69 Tests: (3) GGT (482) GGT 19 U/L 3-90 *3 Tests: (4) COMPREHENSIVE METABOLIC PANEL (10231) GLUCOSE 93 mg/dL 65-99 *4 Went and got injected with radioactive superpowers and scanned yesterday. My PA described the above as 'not extremely elevated, and perhaps nothing given the lack of other complaints". Anyway, thanks for the response, hope its not bone cancer