Is there any evidence to show that Statins decrease in effectiveness the longer you take them?

I’m only 28 but I would like to start statins because my LDL-C is 136 mg/dl(148 last year) and I have a family history(everyone in my family has had heart problems/been on statins). Doctors in my family tell me that if I start now, I would have to increase the dose as I age, essentially that saying that your body becomes “tolerant” to the drug and lower doses stop being effective with time. Is there any truth to this?

No, this is not accurate.

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