Muscle protein synthesis and total daily protein

Nutrition Q&A [Moderated]
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1

Hi,

You’ve likely answered this before but I can’t specifically find where, so asking here.

Muscle protein synthesis has the sweet spot when consuming 20-40g protein every 3-5 hours (assuming ~3g leucine in said protein) - think that’s pretty well fact now?

There’s also ranging theories on the total daily protein in-take 1.6-3.2g protein per kg of bodyweight

Is there, therefore, a point at which the body reaches a protein saturation point in a daily period and that MPS fails to spike as it would usually?

For example, I’m 85kg and focused on gaining strength/mass - targeting ~180g protein per day.

If I were to wake at 5am and consume 40g protein (with ~3g leucine) every 3 hours until 11pm (= 280g daily protein) is there a point at which the MPS rate would diminish or even fail to spike?

Cheers

2

There is a saturation point of dietary protein with respect to muscle protein synthesis- meaning that taking any more protein wouldn’t generate a bigger response.

3

Thanks @Jordan_Feigenbaum